Twenty-one-year-old Megan Cartwright has never been outside the small town she was born in, but one winter's day, in 1966, she leaves everything behind and sets out for London. Ahead of her is a glittering new life, just waiting for her to claim it. But left behind, her family begins to unravel. Disturbing letters from home begin to arrive, and torn between her independence and family ties, Megan must make an impossible choice.

Arthur and Jake are the sons of a farmer in the mid-1930s, when life is tough and another world war is looming. Arthur is solid and dutiful, set to inherit the farm and his father's character; Jake is younger, attractive, mercurial and dangerous to know.

Clara's sister is missing. Angry, rebellious Rose had a row with their mother, stormed out of the house and simply disappeared. Eight-year-old Clara, isolated by her distraught parents' efforts to protect her from the truth, is grief-stricken and bewildered. Liam Kane, newly divorced, newly unemployed, newly arrived in this small northern town, moves into the house next door, a house left to him by an old woman he can barely remember and within hours gets a visit from the police. It seems he's suspected of a crime.

Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing. But it's the early 1960s and her all-male team at Hastings Research Institute take a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant Nobel-prize-nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

From the night she is rescued as a baby out of the flames of a sinking ship, to the day she joins a pair of daredevil pilots looping and diving over the rugged forests of her childhood, to the thrill of flying Spitfires during the war, the life of Marian Graves has always been marked by a lust for freedom and danger. In 1950, she embarks on her life's dream - to fly a Great Circle around the globe, pole to pole. But after a crash landing, she finds herself stranded on the Antarctic ice without enough fuel. 

One by one, she undid each event, each decision, each choice. If Davy had remembered to put on a coat. If Seamie McGeown had not found himself alone on a dark street. If Michael Agnew had not walked through the door of the pub on a quiet night in February in his white shirt. There is nothing special about the day Cushla meets Michael, a married man from Belfast, in the pub owned by her family. But here, love is never far from violence, and this encounter will change both of their lives forever.

Cristabel Seagrave has always wanted her life to be a story, but there are no girls in the books in her dusty family library. For an unwanted orphan who grows into an unmarriageable young woman, there is no place at all for her in a traditional English manor. But from the day that a whale washes up on the beach at the Chilcombe estate in Dorset, and 12-year-old Cristabel plants her flag and claims it as her own, she is determined to do things differently.

When the kids are grown and Mercy Garrett gradually moves herself out of the family home, everyone determines not to notice. Over at her studio, she wants space and silence. She won't allow any family clutter. Not even their cat, Desmond. Yet it is a clutter of untidy moments that forms the Garretts' family life over the decades, from giving a child a ride to a painstaking Easter lunch, a fateful train journey to an unexpected homecoming. And it all begins in 1959, with a family holiday to a cabin by a lake.

Abigail Jex never expected to see any of the Radleys again. They were extraordinary, captivating creatures transplanted from a bohemian corner of North London to outer suburbia, and the young Abigail found herself drawn into their magic circle: the eccentric Frances, her new best friend; Frances' mother, the liberated, headstrong Lexi; and of course the brilliant, beautiful Rad. Abigail thought she'd banished the ghost of her life with them and the catastrophe that ended it, but 13 years later a chance encounter forces her to acknowledge that the spell is far from broken.

Laura, an impoverished Cornish girl, meets her husband when they are both in service in Teignmouth in 1916. They have a baby, Charles, but Laura's husband returns home from the trenches a damaged man, already ill with the tuberculosis that will soon leave her a widow. In a small, class-obsessed town she raises her boy alone, working as a laundress and gradually becomes aware that he is some kind of genius.

1944, in the ruined wine cellar of a Tuscan villa, as bombs fall around them, two strangers meet and share an extraordinary evening. Ulysses Temper is a young British soldier; Evelyn Skinner is a sexagenarian art historian and possible spy. She has come to Italy to salvage paintings from the wreckage and relive memories of the time she encountered EM Forster and had her heart stolen by an Italian maid in a particular Florentine room with a view.

Texas, 1934. Elsa Martinelli had finally found the life she’d yearned for. A family, a home and a livelihood on a farm on the Great Plains. But when drought threatens all she and her community hold dear, Elsa’s world is shattered to the winds. Fearful of the future, when Elsa wakes to find her husband has fled, she is forced to make the most agonizing decision of her life. Fight for the land she loves or take her beloved children, Loreda and Ant, west to California in search of a better life. Will it be the land of milk and honey? 

Everyone tells Martha Friel she is clever and beautiful, a brilliant writer who has been loved every day of her adult life by one man, her husband Patrick. So why is everything broken? Why is Martha - on the edge of 40 - friendless, practically jobless and so often sad? And why did Patrick decide to leave? Maybe she is just too sensitive, someone who finds it harder to be alive than most people. Or maybe - as she has long believed - there is something wrong with her. 

In the 1960s, Florence, a pregnant 16-year-old, is banished to one of the remotest parts of the UK. Years later, Nell and Dougie are both at critical moments in their lives when their paths cross. Sometimes who we are goes way beyond where we are from. What happened to Florence? Why is Dougie so reluctant to return home? How can Nell make peace with the lies she's been told? 

It is 1953. Thomas Wazhushk is the night watchman at the first factory to open near the Turtle Mountain Reservation in rural North Dakota. He is also a prominent Chippewa Council member, trying to understand a new bill that is soon to be put before Congress. The US Government calls it an 'emancipation' bill but it isn't about freedom - it threatens the rights of Native Americans to their land, their very identity. How can he fight this betrayal?