Genetic History

This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is for every one of the 100 billion modern humans who has ever drawn breath. But it is also our collective story, because in each of our genomes we carry the history of the whole of our species.

An almost limitless archive of our history lies hidden inside our bodies, and this book traces the ancient story of Scotland from that scientific viewpoint. The mushrooming of genetic studies, of DNA analysis, is rewriting history in spectacular fashion. In Scotland: A Genetic Journey, Alistair Moffat explores the history that is printed on our genes, and in a remarkable new approach, uncovers the detail of where Scots are from, where they have journeyed, and who they are - and in so doing, vividly colors in a DNA map of Scotland.

What is human consciousness, and how is it possible? This question fascinates thinking people from poets and painters to physicists, psychologists, and philosophers. From Bacteria to Bach and Back is Daniel C. Dennett's brilliant answer, extending perspectives from his earlier work in surprising directions, exploring the deep interactions of evolution, brains, and human culture.

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies - far from the out-of-control nightmare depicted in science fiction - have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

From that first foray to the spread of early hominids who later became Homo sapiens, life has persisted, undaunted. A (Very) Short History of Life is an enlightening story of survival, of persistence, illuminating the delicate balance within which life has always existed, and continues to exist today. It is our planet like you’ve never seen it before. Life teems through Henry Gee’s lyrical prose - colossal supercontinents drift, collide and coalesce, fashioning the face of the planet as we know it today.

How did we get here? All cultures have a creation story, but a little over 150 years ago, Charles Darwin introduced a revolutionary new one. We, and all living things, exist because of the action of evolution on the first simple life form and its descendants. In How Evolution Explains Everything About Life, leading biologists and New Scientist take you on a journey of a lifetime, exploring the questions of whether life is inevitable or a one-off fluke and how it got kick-started.

The Gene is the story of one of the most powerful and dangerous ideas in our history, from best-selling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a 'unit of heredity'.

Palaeontologist Steve Brusatte weaves together the history and evolution of our mammal forebears with stories of the scientists whose fieldwork and discoveries underlie our knowledge, both of iconic mammals like the mammoths and sabre-toothed tigers of which we have all heard, and of fascinating species that few of us are aware of. For what we see today is but a very limited range of the mammals that have existed; in this fascinating and groundbreaking book, Steve Brusatte tells their—and our—story.

In Native American DNA, Kim TallBear shows how DNA testing is a powerful - and problematic - scientific process that is useful in determining close biological relatives. But tribal membership is a legal category that has developed in dependence on certain social understandings and historical contexts, a set of concepts that entangles genetic information in a web of family relations, reservation histories, tribal rules, and government regulations.

In a book that is both groundbreaking and accessible, Daniel C. Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet", focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

Charles Darwin’s theories, first published more than 150 years ago, still set the paradigm of how we understand the evolution of life--but scientific advances of recent decades have radically altered that. Now two pioneering scientists draw on their years of experience in paleontology, biology, chemistry, and astrobiology to deliver an eye-opening narrative using a generation’s worth of insights culled from new research.

Here is the extraordinary story of the unfolding of life on Earth, told by Michael J. Benton, a world-renowned authority on biodiversity. Ranging over four billion years, Benton weaves together the latest findings on fossils, earth history, evolutionary biology, and many other fields to highlight the great leaps that enabled life to evolve from microbe to human - big breakthroughs that made whole new ways of life possible - including cell division and multicellularity, hard skeletons, the move to land, the origin of forests, the move to the air.

Humanity has often found itself on the precipice. We've survived and thrived because we've never stopped moving. In this eye-opening book, Johannes Krause, chair of the Max Planck Institute for the History of Humanity, offers a new way of understanding our past, present and future. Marshalling unique insights from archaeogenetics, an emerging new discipline that allows us to read our ancestors' DNA like journals chronicling personal stories of migration, Krause charts two millennia of adaption, movement and survival.

How did life begin? It is perhaps the most important question science has ever asked. Over the centuries, the search for an answer has been entwined with some of science's most revolutionary advances, including van Leeuwenhoek's microscope, Darwin's theory of evolution, and Crick and Watson's unveiling of DNA.