In 1976, four students took a trip to the desert. Now the repercussions of that fateful summer are coming back to haunt them. And repercussions are just what Guy doesn't need: his wife, Jane, is moving swiftly from slightly eccentric to downright peculiar, their three-year-old daughter seems set on destroying Jane's sanity, and now even God's gone quiet on him. As for Nina, she's having enough trouble with her son, James. He's got exams looming, a new girlfriend with pneumatic breasts, and now, it seems, he's on drugs. Nina certainly won't welcome any ghosts from the past.

Abigail Jex never expected to see any of the Radleys again. They were extraordinary, captivating creatures transplanted from a bohemian corner of North London to outer suburbia, and the young Abigail found herself drawn into their magic circle: the eccentric Frances, her new best friend; Frances' mother, the liberated, headstrong Lexi; and of course the brilliant, beautiful Rad. Abigail thought she'd banished the ghost of her life with them and the catastrophe that ended it, but 13 years later a chance encounter forces her to acknowledge that the spell is far from broken.

On the brink of 40, newly single with a failed business, Philip thought he'd reached an all-time low. It only needed a discarded chip on a South London street to lay him literally flat. So, bedbound and bored, Philip naturally starts to write the story of his life. But between the mundane catalogue of seaside holidays and bodged DIY, broken relationships and unspoken truths, more surprises are revealed, both comic and touching, than Philip or his family ever bargained for. Even, perhaps, a happy ending.

When the kids are grown and Mercy Garrett gradually moves herself out of the family home, everyone determines not to notice. Over at her studio, she wants space and silence. She won't allow any family clutter. Not even their cat, Desmond. Yet it is a clutter of untidy moments that forms the Garretts' family life over the decades, from giving a child a ride to a painstaking Easter lunch, a fateful train journey to an unexpected homecoming. And it all begins in 1959, with a family holiday to a cabin by a lake.

Without even noticing, Esther Fairchild has become locked into routine. Living with her adored brother, Christian, she divides her time between illustrating children's books, nightly shifts as a waitress, weekly visits to her father and fortnightly meetings with her married lover. Then one day she encounters a face in the crowd which jolts her out of her mundane existence and makes her question both her life and the past that has helped to shape it.

Susan and Norma have been best friends for years, at first thrust together by force of circumstance (a job at The Pin Cushion, a haberdashery shop in 1990s Leicestershire) and then by force of character (neither being particularly inclined to make friends with anyone else). But now, 30 years later, faced with a husband seeking immortality and Norma out of reach on a wave of professional glory, Susan begins to wonder whether she has made the right choices about life, love, work and, most importantly, friendship.

After 20 years of contentedly playing the role of home-maker and mother, Frances Copeland's life is shattered by the sudden death of her husband. With no career to fall back on and her son and daughter leaving home, the solitude of bereavement hits particularly hard. When new love beckons, in the form of a handsome young man 15 years her junior, Frances is torn. She longs to open her heart again but does not dare to trust her feelings. Turning to her closest friends for help, she is met by a wall of judgemental attitudes and envy.

Laura, an impoverished Cornish girl, meets her husband when they are both in service in Teignmouth in 1916. They have a baby, Charles, but Laura's husband returns home from the trenches a damaged man, already ill with the tuberculosis that will soon leave her a widow. In a small, class-obsessed town she raises her boy alone, working as a laundress and gradually becomes aware that he is some kind of genius.

Twenty-one-year-old Megan Cartwright has never been outside the small town she was born in, but one winter's day, in 1966, she leaves everything behind and sets out for London. Ahead of her is a glittering new life, just waiting for her to claim it. But left behind, her family begins to unravel. Disturbing letters from home begin to arrive, and torn between her independence and family ties, Megan must make an impossible choice.

Everyone tells Martha Friel she is clever and beautiful, a brilliant writer who has been loved every day of her adult life by one man, her husband Patrick. So why is everything broken? Why is Martha - on the edge of 40 - friendless, practically jobless and so often sad? And why did Patrick decide to leave? Maybe she is just too sensitive, someone who finds it harder to be alive than most people. Or maybe - as she has long believed - there is something wrong with her. 

Orphaned young, Kate Morrison was her older brother Matt's protégé, her curious fascination for pond-life fed by his passionate interest in the natural world. Now a zoologist, she can identify organisms under a microscope but seems blind to the tragedy of her own emotional life. She thinks she's outgrown her family, who were once her entire world - but she can't seem to outgrow her childhood or lighten the weight of their mutual past.

To Nicole and Jamie Maguire, their parents seem the ideal couple - a suburban double act, happily married for more than 30 years. So when Linda and Gerry announce that they've decided to separate, the news sends shockwaves through the siblings' lives, forcing them to confront their own expectations and desires. 

1944, in the ruined wine cellar of a Tuscan villa, as bombs fall around them, two strangers meet and share an extraordinary evening. Ulysses Temper is a young British soldier; Evelyn Skinner is a sexagenarian art historian and possible spy. She has come to Italy to salvage paintings from the wreckage and relive memories of the time she encountered EM Forster and had her heart stolen by an Italian maid in a particular Florentine room with a view.

As Charles Redfern lies motionless in hospital, his wife, Anne, and daughter, Charlotte, are forced to confront their relationships with him - and with each other. Anne, once beautiful and clever, has paled in the shadow of her husband's dominance. Charlotte, meanwhile, is battling with her own inner darkness and is desperate to prevent her relationship with her not-yet-divorced lover from disintegrating.

Yasmin Ghorami has a lot to be grateful for: a loving family, a fledgling career in medicine and a charming, handsome fiancé, fellow doctor Joe Sangster. But as the wedding day draws closer and Yasmin's parents get to know Joe's firebrand feminist mother, both families must confront the unravelling of long-held secrets, lies and betrayals. As Yasmin dismantles her own assumptions about the people she holds most dear, she's also forced to ask herself what she really wants in a relationship and what a 'love marriage' actually means.