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The Breakthrough cover art

The Breakthrough

By: Charles Graeber
Narrated by: Will Collyer, Charles Graeber
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Summary

New York Times best-selling author Charles Graeber tells the astonishing story of the group of scientists working on a code that can enable the human immune system to fight - and perhaps even cure - cancer. 

For decades, scientists have puzzled over one of medicine’s greatest mysteries: why doesn’t our immune system fight cancer the way it does other diseases? The answer is a series of tricks that cancer has developed to turn off normal immune responses - tricks that scientists have only recently discovered and now are learning to defeat. We are in the midst of a revolution in our understanding of cancer and how to beat it. 

Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing and Nobel Prize-winning scientific discoveries that unleash our natural ability to recognise and defeat cancer, as told through the experiences of the patients, physicians, and immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, and the definitive account of a historic moment in medical science.

©2018 Charles Graeber (P)2019 Hachette Audio

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Loved it

I am a stage 4 cancer fighter and avid amateur researcher on the subject and this book has really struck a cord with me. I often wonder what is taking so long to cure this thing and this book goes along way to answering that question while brilliantly tying it to personal stories. It also gives massive hope for the future and highlights how quickly things are now moving. You need a good understanding of cancer at a molecular level but if your interested in the subject - it’s well worth the listen. Excellent

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Very good

If you are interested in immunotherapy then this is an excellent listen for the layman.

For anyone interested in the new therapies like CAR-T and checkpoint inhibitors, then the story of how they were developed and an ordinary person's explanation of how they work is in here.

I'm pleased I listened. If I have a minor gripe then I think it could easily be an hour shorter without omitting anything of importance. Overall it's a good and informative book.

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Immunotherapy

Great high level history and review of immunotherapy. Really interesting stories and science. Recommended for any with an interest in the area.

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